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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
U2AF2
All Species:
10.91
Human Site:
S41
Identified Species:
21.82
UniProt:
P26368
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26368
NP_001012496.1
475
53501
S41
S
R
D
R
K
R
R
S
R
S
R
D
R
R
N
Chimpanzee
Pan troglodytes
XP_530073
713
78555
H158
I
G
G
V
S
K
W
H
L
R
K
E
P
K
H
Rhesus Macaque
Macaca mulatta
XP_001091568
467
51268
R37
G
V
R
P
L
S
P
R
G
D
Q
E
P
A
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P26369
475
53499
S41
S
R
D
R
K
R
R
S
R
S
R
D
R
R
N
Rat
Rattus norvegicus
Q63285
419
46487
G20
P
R
F
L
E
A
F
G
R
L
W
Q
V
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080595
456
51328
R39
S
K
S
K
E
R
K
R
R
S
R
S
K
E
R
Zebra Danio
Brachydanio rerio
NP_991252
475
53612
R44
S
R
S
R
S
R
E
R
K
R
R
S
R
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24562
416
46636
S17
R
E
R
R
R
H
R
S
R
S
R
D
R
H
R
Honey Bee
Apis mellifera
XP_623055
432
48801
S30
D
R
D
R
R
H
R
S
R
S
R
D
R
R
K
Nematode Worm
Caenorhab. elegans
P90978
496
55412
R76
R
D
T
R
R
R
S
R
S
R
D
R
G
E
R
Sea Urchin
Strong. purpuratus
XP_001189425
444
50005
R33
S
R
S
R
E
R
R
R
R
S
R
S
K
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L716
589
66297
H147
D
R
D
R
E
V
R
H
R
R
R
S
R
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.4
87.5
N.A.
N.A.
99.7
20
N.A.
N.A.
N.A.
92
86.3
N.A.
66.7
66.7
51.4
62.9
Protein Similarity:
100
57.2
89.2
N.A.
N.A.
99.7
37.6
N.A.
N.A.
N.A.
94.7
92.2
N.A.
77
77.8
62.5
75.5
P-Site Identity:
100
0
0
N.A.
N.A.
100
13.3
N.A.
N.A.
N.A.
33.3
40
N.A.
53.3
73.3
13.3
53.3
P-Site Similarity:
100
33.3
20
N.A.
N.A.
100
33.3
N.A.
N.A.
N.A.
66.6
46.6
N.A.
60
80
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
34
0
0
0
0
0
0
9
9
34
0
0
0
% D
% Glu:
0
9
0
0
34
0
9
0
0
0
0
17
0
25
0
% E
% Phe:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
9
0
0
0
0
9
9
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
17
0
17
0
0
0
0
0
9
9
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
9
17
9
9
0
9
0
9
0
17
9
9
% K
% Leu:
0
0
0
9
9
0
0
0
9
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% N
% Pro:
9
0
0
9
0
0
9
0
0
0
0
0
17
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
9
0
9
0
% Q
% Arg:
17
59
17
67
25
50
50
42
67
34
67
9
50
25
42
% R
% Ser:
42
0
25
0
17
9
9
34
9
50
0
34
0
17
17
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
9
0
9
0
9
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _